44th Annual Oak Ridge Conference - Online Manual



Emerging Technologies for
21
st Century Diagnostics


Thursday, April 19, 2012

KEYNOTE PRESENTATION
Integration of Automated Biosensor Systems for Point-of-Use
Frances S. Ligler
The Center for Bio/Molecular Science and Engineering
Naval Research Laboratory
Washington, D.C.

Nanopore Detectors: Coupling Nanopores to DNA Polymerases for DNA Analysis
Mark Akeson
University of California-Santa Cruz
Santa Cruz, Calif.

Computational Fluid Dynamical Simulations of Droplet Flow and Merger in Microfluidic Channels
Bradley Stone
San José State University
San José, Calif.

An Integrated Device for Molecular Detection of Pathogens
Haim Bau
University of Pennsylvania
Philadelphia, Pa.

CONTRIBUTED PAPERS
Portable microfluidic chip for detection of Escherichia coli in produce and blood.
Utkan Demirci
Harvard-MIT/HST
Boston, Mass.

Evaluation of a microfluidic system for performance of fully automated companion diagnostics for personalized medicine.
Richard Montagna
Rheonix, Inc.

Ithaca, N.Y.

SESSION II: Emerging Diagnostic Technologies using Mass Spectrometry
Top Down Proteomics: The Case for Whole Protein Mass Spectrometry
Neil L. Kelleher
Northwestern University
Evanston, Ill.

Mass Cytometry: A Massive Step towards More Precise, Single-Cell State Analysis
Scott Tanner
DVS Sciences, Inc.
Markham, Ontario

Molecular Imaging of Tissue Sections by Mass Spectrometry: Looking Beyond the Microscope
Erin Seeley
Vanderbilt University
Nashville, Tenn.

CONTRIBUTED PAPERS
Mass Spectrometric immunoassay for the determination of clinically relevant target protein variants.
Eric Niederkofler
Thermo Fisher Scientific

Tempe, Ariz.

Rapid, Sensitive Dose Assessment for Public Health Emergencies
Lynne Wathen
U.S. Dept. of Health and Human Services
Washington, D.C.

Friday, April 20, 2012

SESSION III: Innovative Technologies for Pathogen Diagnostics

Informatics and Single-Molecule Detection for Rapid Triage of Patients during a Public Health Emergency
Pejman Naraghi-Arani
Lawrence Livermore National Laboratory
Livermore, Calif.

Photo-induced Polymerization Detection: A Method for Rapid, Inexpensive Influenza Virus Characterization with Surveillance Applications 
Michael Artinger
INDEVR, Inc.
Boulder, Colo.

Quantitative, Multiplex Pathogen Detection Using Proximity-dependent DNA Ligation
Cor Schoen
Plant Research International
Wageningen, The Netherlands

CONTRIBUTED PAPERS

Automated Multichannel System for Broadband Detection and Identification of Pathogens.
Rudolf Gilmanshin
Pathogenetix
Woburn, Mass.

A Rapid, Sensitive Chip-based Assay for Detection of rpoB Gene Mutations Conferring Rifampin Resistance in Mycobacterium tuberculosis.
Wanyuan Ao
Great Basin Corporation
Salt Lake City, Utah.

SESSION IV: New Point-of-Care Technologies for the Developing and Developed World

Understanding User Needs in Low-Resource Settings for Diagnostics Development
Roger B. Peck
PATH
Seattle, Wash.

In Vitro Diagnostic Platforms for the Developing World
David Kelso
Northwestern University
Evanston, Ill.

A Test Platform for Lab Quality Nucleic Acid Testing at the Point-of-Care
Eugen Ermantraut
Alere Technologies GmbH
Jena, Germany

CONTRIBUTED PAPERS

Development of a point-of-care rapid and sensitive bacteremia diagnostic.
Alexis Sauer-Budge
Fraunhofer CMI
Brookline, Mass.

Toward low-cost affinity reagents: Yeast-scFv bioprobes specific for pathogen antigens
Gerard Cangelosi
Seattle Biomedical Research Institute
Seattle, Wash.

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