Low-density lipoprotein (LDL cholesterol, LDL-C) is one type of lipoprotein that carries cholesterol in the blood. LDL-C consists mostly of cholesterol and similar substances with a small amount of protein. Most often, this test involves using a formula to calculate the amount of LDL-C in blood based on results of a lipid profile. Occasionally, LDL-C is measured directly.
Of all the forms of cholesterol in the blood, the LDL cholesterol is considered the most important form in determining risk of heart disease. Since treatment decisions are often based on LDL values, this test may be used to monitor levels after the start of diet or exercise programs or to determine whether or not prescribing one of the lipid-lowering drugs, such as statins, would be useful.
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John Contois, PhD, DABCC, FACB
Dr. Contois currently works in the in vitro diagnostics industry, and previously worked for many years as a laboratory director in both commercial and hospital laboratories. He is certified as a diplomate of the American Board of Clinical Chemistry and a fellow of the Academy of Clinical Biochemistry. His current research focuses on the development of innovative products for the clinical laboratory including stable lipid quality control material and novel assays for cardiovascular disease risk assessment. He has authored or coauthored more than 40 peer-reviewed articles and book chapters, and is active on a variety of professional committees, including the Lipoprotein and Vascular Diseases Division Executive Committee for AACC. He serves on the editorial boards of The Fats of Life--the AACC Lipoproteins and Vascular Diseases newsletter--Clinica Chimica Acta, and the Journal of Clinical Lipidology, and previously served as Associate Editor of The Fats of Life from 2004 to 2009.
1) LDL-C association with cardiovascular events
2) Current guidelines for LDL-C testing
3) How LDL-C is used in CVD risk assessment and treatment decisions
4) Direct LDL-C vs. calculated LDL-C
5) Importance of non-HDL cholesterol
This webcast is intended for laboratory administrators, directors, and managers; pathologists; and IVD industry professionals involved in the research, development or performance of LDL cholesterol assays.
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