Tandem Mass Spectrometry in the Clinical Laboratory

Mass Spec Image



Earn 12 ACCENT® continuing education credits and a certificate of completion for successfully completing the program before the access end date.

The program is composed of ten courses, listed below. Each course can be completed online in 1-3 hours and contains a lecture, slides and transcripts, and a quiz. Some include additional readings and practice exercises. Communicate questions or comments using the program discussion board.

  • Introduction
  • Basics of Mass Spectrometry Theory
  • Basics of Liquid Chromatography Theory
  • Setting up a Clinical Mass Spectrometry Laboratory
  • Maintenance and Troubleshooting of LC-MS/MS
  • Making Accurate Calibrators and High Purity Reagents for LC-MS/MS Methods
  • Principles and Best Practices for Quantitation Using LC-MS/MS
  • Validation of LC-MS/MS Methods
  • Tips for Achieving and Maintaining Consistent High Quality Production in a Clinical Mass Spectrometry Laboratory
  • Gas Chromatography-Mass Spectrometry (GC-MS) in Clinical Laboratories

Certificates are awarded online upon successful completion of the program. Graduates are recognized on a register located on the certificate program web page.


This program was developed to provide laboratorians with an understanding of ten different areas within mass spectrometry. Developed with all levels of laboratory professionals in mind, the content of this program is at the basic to intermediate level and will provide participants with opportunities to increase their knowledge of mass spectrometry. The faculty recognizes the nuances of training within the field and worked to provide participants with important tips and hints for practical application within their own laboratories.

After completing this program, participants will be able to:

  • Understand and apply the basic principles of chromatography and mass spectrometry theory that are needed for routine operation of clinical mass spectrometry systems
  • Be familiar with common maintenance protocols and troubleshooting procedures for LC-MS/MS instruments, including practical tips for obtaining consistent, high-quality results in a clinical laboratory service environment
  • List six important steps to take in preparing for installation of an LC-MSMS instrument and start-up of a clinical mass spectrometry laboratory
  • Describe detailed steps for preparing accurate standards, high purity reagents, CAP compliant validation protocols, and precise quantitation procedures for LC-MSMS methods

These expert faculty and educators developed and contributed to the content in this program:

  • Judith Stone, PhD, DABCC, MT (ASCP), Faculty Chair
    University of California San Diego, San Diego, CA
  • Uttam Garg, PhD
    Childrens’ Mercy Hospital, Kansas City, MO
  • Elizabeth Pattison, BS, ASCP
    ARUP Laboratories, Salt Lake City, UT
  • Douglas Stickle, PhD, DABCC
    Jefferson University Hospital, Philadelphia, PA

This certificate program is supported by AB SCIEX and the Waters Corporation.


    Open Enrollment Until December 31, 2014
    Program Access from January 1, 2014 until July 15, 2015

    Fee: $275 AACC Member/$550 Non-member
    Course Number: 8736
    12 ACCENT® continuing education credits

    • If you purchase the program on our website, processing is immediate and the login information will be on your AACC Web Orders confirmation email.
    • If you purchase the program over the telephone, order processing will take 3-4 business days. Access information will be emailed to you upon processing completion/enrollment.
    • If you purchase the program via US Post or fax, please allow 2 weeks for order processing.
    • Haven’t received your access information? Please contact AACC Customer Service.  


    ACCENT® credit is offered. AACC is an approved provider of continuing education for clinical laboratory scientists in the states of California, Florida, Louisiana, Montana, Nevada, North Dakota, Rhode Island, and West Virginia.

Page Access:

General Information


Technical Requirements

Cancellation Policy

Register for Program

Already Registered?

Bsck to Programs







This certificate program is supported by AB Sciex and the Waters Corporation.